N-[2-(METHYLSULFONYL)ETHOXYCARBONYLOXY]SUCCINIMIDE

N-[2-(METHYLSULFONYL)ETHOXYCARBONYLOXY]SUCCINIMIDE - Names and Identifiers

Name	2,5-dioxopyrrolidin-1-yl (2-(methylsulfonyl)ethyl) carbonate
Synonyms	MSC-ONSU 2-(METHANESULFONYL)ETHYL SUCCINIMIDYL CARBONATE 2-(METHYLSULFONYL)ETHYL N-SUCCINIMIDYL CARBONATE 2-(Methanesulfonyl)ethyl N-succinimidyl carbonate N-[2-(METHYLSULFONYL)ETHOXYCARBONYLOXY]SUCCINIMIDE 2,5-dioxopyrrolidin-1-yl (2-(methylsulfonyl)ethyl) carbonate N-[2-(Methylsulfonyl)ethoxycarbonyloxy]succinimide, MSC-ONSu
CAS	57903-15-8

N-[2-(METHYLSULFONYL)ETHOXYCARBONYLOXY]SUCCINIMIDE - Physico-chemical Properties

Molecular Formula	C8H11NO7S
Molar Mass	265.24
Density	1.53±0.1 g/cm3(Predicted)
Melting Point	115-118°C(lit.)
Boling Point	458.5±47.0 °C(Predicted)
Storage Condition	2-8°C

N-[2-(METHYLSULFONYL)ETHOXYCARBONYLOXY]SUCCINIMIDE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
FLUKA BRAND F CODES	10-21

N-[2-(METHYLSULFONYL)ETHOXYCARBONYLOXY]SUCCINIMIDE - Introduction

2-(Methanesulfonyl) ethyl succinimidyl carbonate (MSC-ONSU) is an organic compound with the chemical formula C8H11NO8S and a molecular weight of 281.24g/mol.

Nature:
1. appearance: colorless or yellowish liquid.
2. melting point:-5 ~ -10°C
3. Boiling point: 140~150°C (760 mmHg)

Use:
MSC-ONSU is an active chemical based on carbonate, which is mainly used in organic synthesis reactions, such as esterification, acylation, and hydroxyacylation. It is widely used in the synthesis of new drugs, pesticides, dyes and functional materials.

Preparation Method:
The preparation of MSC-ONSU is generally carried out by the following steps:
1. reacting methanesulfonic acid with succinimide in the presence of sulfuryl chloride or brominated sulfoxide to generate methanesulfonimide acylate;
2. The methylsulfonyl imide acylate is reacted with dimethyl carbonate under alkaline conditions to generate MSC-ONSU.

Safety Information:
1. MSC-ONSU is a kind of organic matter, in the operation or storage should avoid exposure to fire or high temperature.
2. in the operation, need to take the necessary protective measures, such as wearing protective glasses, wearing protective gloves.
3. When in contact with skin or eyes should immediately rinse with water, and seek medical help.
4. during storage and transportation, ensure that the container is well sealed and away from fire and oxidant.

Last Update：2024-04-10 22:29:15